cov khoom

Nitric Oxide yog dab tsi?

Nitric oxide yog cov roj uas tsim los ntawm cov hlwb uas cuam tshuam nrog kev ua xua lossis eosinophilic hawb pob.

FeNO yog dab tsi?

Kev ntsuas Fractional exhaled Nitric Oxide (FeNO) yog ib txoj hauv kev los ntsuas tus nqi ntawm nitric oxide hauv qhov ua pa tawm.Qhov kev sim no tuaj yeem pab kuaj mob hawb pob los ntawm kev qhia txog qib ntawm kev mob hauv lub ntsws.

Clinical Utility ntawm FeNO

FeNO tuaj yeem muab cov kev pabcuam uas tsis muaj kev cuam tshuam rau kev kuaj pom thawj zaug ntawm kev mob ntsws asthma nrog ATS thiab NICE qhia nws ua ib feem ntawm lawv cov lus qhia tam sim no thiab kev kuaj mob algorithms.

Cov ntawv luv: ATS, American Thoracic Society;FeNO, fractional exhaled nitric oxide;GINA, Ntiaj teb no Initiative rau Asthma;ICS, nqus tau corticosteroid;NICE, National Institute for Health and Care Excellence.

Cov txheej txheem ATS txhais cov qib siab, nruab nrab, thiab qis FeNO hauv cov neeg laus li> 50 ppb, 25 txog 50 ppb, thiab <25 ppb, feem.Thaum nyob hauv cov menyuam yaus, qib siab, nruab nrab, thiab qis FeNO tau piav qhia raws li> 35 ppb, 20 txog 35 ppb, thiab <20 ppb (Table 1).ATS pom zoo kom siv FeNO los txhawb kev kuaj mob ntsws asthma qhov twg cov ntaub ntawv pov thawj xav tau, tshwj xeeb hauv kev kuaj mob eosinophilic o.ATS piav qhia tias qib FeNO siab (> 50 ppb hauv cov neeg laus thiab> 35 ppb hauv cov menyuam yaus), thaum txhais hauv cov ntsiab lus kho mob, qhia tias eosinophilic o tuaj nrog corticosteroid teb rau cov neeg mob cov tsos mob, thaum qib qis (<25 ppb hauv cov laus. thiab <20 ppb hauv cov menyuam yaus) ua rau qhov tsis zoo no thiab theem nrab yuav tsum tau txhais nrog ceev faj.

Tam sim no NICE cov lus qhia, uas siv qis FeNO txiav tawm ntau dua ATS (Table 1), pom zoo kom siv FeNO ua ib feem ntawm kev kuaj mob ua haujlwm txog qhov kev kuaj mob hawb pob raug txiav txim siab rau cov neeg laus lossis qhov chaw kuaj mob tsis paub tseeb hauv cov menyuam yaus.FeNO qib tau rov txhais dua hauv cov ntsiab lus kho mob thiab kev sim ntxiv, xws li kev kuaj mob bronchial provocation tuaj yeem pab kuaj mob los ntawm kev ua kom pom cov pa ua pa.GINA cov lus qhia lees paub lub luag haujlwm ntawm FeNO hauv kev txheeb xyuas eosinophilic o hauv mob hawb pob tab sis tam sim no tsis pom lub luag haujlwm rau FeNO hauv kev kuaj mob hawb pob algorithms.Scottish Consensus txhais cov kev txiav tawm raws li steroid raug nrog cov txiaj ntsig zoo ntawm> 40 ppb hauv cov neeg mob steroid-naive thiab> 25 ppb rau cov neeg mob ntawm ICS.